It depends on what kind of skin do you have. Oily, dry, chapped, ect.
I personally have very oily skin (and at random times it would be very dry). and have tried many treatments such as, Neutrogena, Clearasil, Clinique, Noxzema, and Proactiv (which I'm currently using at the moment).
But I've also done simple treatments that you can do straight at home without the needs for buying a product. Although, that doesn't mean it can be a substitute for the product that you are using, it just helps you make your pores smaller and cleaner. For example:
If you have a white blemish, take an ice cube and press it against the pimple in a circular motion (also, don't leave the ice cube on your pimple for too long, because you can possibly get a freezer burn). The chill from the ice helps reduce inflaming in the pimple and shrinks the spot. Then wash your face with the regular products you normally use. It's also something for temporary use, only when you need to, really. It's not something to do as part of your daily schedule.
I used to use the Neutrogena Wave, I think it does work, but it doesn't seem to be a product that should be used by itself. It did make my skin softer and made it look fresher, but I always used a different product (after I washed my face).
Clearasil, I do not enjoyyyy.... -.-
It didn't do very much for my skin, it just seemed to sit there, it didn't make my face worse nor better. It was just there.
Clinique I used for a while, my mom uses it so that's how I find out about it. It's a good product depending on your skin. Although sometimes my skin would inflame, because it made my skin too dry (I used the bar of soap). It's best to use it when you are taking a shower (if you have the bar of soap; Face and shoulders only), after you washed your hair.
I heard about Noxzema from my older sister. It's a good product and it clears your skin well, but after a few weeks of using it my face became inflamed (Also, it has a very strong smell. Bewareee...).
I am now currently using Proactiv and I personally adore it, it does clear up my skin, and it gives it the right nutrients it needs. Although, just like any product in the world blemishes clear up in practically a month. The problem with Proactiv though, is when you first use it may make your pimples worse, but then after a while it clears up amazingly. Also, you cannot skip a day when using proactiv, or else the blemishes will come back the next day.
I always have to get myself to wash my face, because sometimes I just have time, or I really just don't want to get up and do it. I'm too lazy. But you gotta be committed to cleaning your face when you wake up and before you go to sleep. I also have to force myself not to touch my face, because I have that horrible habit.
*~Also~*
These are just my personal experiences with those products, everyone's skin is different, hence, all skin may react differently.