Two movies to disappoint me recently were:

1.Sanctuary, where the quote comes from
2. The Island of Doctor Moreau (1996)

Sanctuary was a good laugh at how terrible it was but the last few minutes ruined it for me.

The Island of Doctor Moreau, I had high expectations for this movie based on an H.G. Wells movie. I believe that it could be redone again with updated graphics and more into genetic splicing making more monstrous creatures