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The DNA-protein paradox has long been a point of contention in the origin of life debate. Since nucleic acids (DNA and RNA) are necessary for protein production, and protein carries out nucleic acid production, a primitive cell could not exist without the simultaneous existence of both types of molecules and a system for faithful replication. Faced with this challenging hurdle, evolutionists countered with the RNA World Hypothesis, which proposes that RNA once performed the dual roles of information carrier and catalyst in primitive cells, with those roles eventually being largely handed over to DNA and protein. Admittedly, the RNA World Hypothesis generates its own set of paradoxes that are similarly troubling, some of which are the focus of current origins research. However, aside from the DNA-protein paradox and its fallouts, what is not generally acknowledged is that there are a plethora of other distinct paradoxes in cell and molecular biology that present equally insurmountable obstacles to the naturalistic origin of life. The purpose of this review is to reveal these paradoxes, describe their significance, and evaluate the rebuttals that exist from the scientific community.
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